QuickView for coagulation factor ix;jsessionid=CA515EF582DC7A3796FE273B35DDD29B;jsessionid=D07DC7F2F6D44855765180DFCC1C71BB;jsessionid=5D4E62601A08041E9E3D98BD5A4149A9 (gene)

Gene Symbol:

F9 Mus musculus

Full name:

coagulation factor IX

Synonyms:

AW111646, Cf-9, Cf9, coagulation factor IX, christmas factor

Genomic Location:

Chr X: 57252641-57283935

Description:

This gene encodes a vitamin K-dependent serine protease that plays a critical role in the intrinsic pathway of blood coagulation. The encoded protein is an inactive zymogen that is activated by coagulation factor XIa to generate factor IXa, a heterodimer containing heavy and light chains. In association with factor VIII, membrane phospholipids and ...

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This gene encodes a vitamin K-dependent serine protease that plays a critical role in the intrinsic pathway of blood coagulation. The encoded protein is an inactive zymogen that is activated by coagulation factor XIa to generate factor IXa, a heterodimer containing heavy and light chains. In association with factor VIII, membrane phospholipids and calcium ions, factor IXa cleaves the inactive zymogen factor X to generate active factor Xa. Genetic deletion of this gene in mice results in a severe bleeding phenotype. Alternative splicing of this gene results in multiple transcript variants.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CEBPB_01 ,  STAT_01 ,  STAT5A_01 ,  STAT5B_01 ,  STAT5A_03 ,  STAT6_01 ,  STAT_Q6 ,  CEBP_Q2_01 ,  TGGNNNNNNKCCAR_UNKNOWN ,  YATTNATC_UNKNOWN ,  TGTTTGY_HNF3_Q6 ,  TGGAAA_NFAT_Q4_01 ,  TTCYNRGAA_STAT5B_01

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